We compare the partial least squares (PLS) and the principal component
analysis (PCA), in a general case in which the existence of a true li
near regression is not assumed. We prove under mild conditions that PL
S and PCA are equivalent, to within a first-order approximation, hence
providing a theoretical explanation for empirical findings reported b
y other researchers. Next, we assume the existence of a true linear re
gression equation and obtain asymptotic formulas for the bias and vari
ance of the PLS parameter estimator.