COMPARATIVE EXPERIMENTAL-STUDY OF 10-PERCENT AND 15-PERCENT MEDICAL GELATIN IN THE ANTERIOR-CHAMBER AND IN THE POSTERIOR EYE SEGMENT AS A VISCOSUBSTANCE IN THE VISCOSURGERY

This article discusses the possibility of application of 15% medical g elatin solution compared to 10% medical gelatin solution in the anteri or chamber and in the posterior eye segment as a viscosubstance in the viscosurgery. The experimental investigations were performed on 24 Ch inchilla rabbits, divided in two groups consisting of 12 each, 0.5 mi of 10% and 15% of medical gelatin were injected in the anterior chambe r and 2 mi of 10% and 15% medical gelatin were injected in the vitreou s body of the tested eyes. 2% methyl cellulose and 0.89% Sodium Chlori de were injected in the vitreous body of the control eyes. Clinical, b iomicroscopical, ophthalmoscopical, tonometrical, histological and ele ctron-microscopical examinations were performed. It was established th at when the eyes were injected with 10% and 15% medical gelatin, as we ll as with 0.89% Sodium Chloride, the intraocular pressure was not inc reased but when the eyes were injected with methyl cellulose the intra ocular pressure was increased. We also found that 15% of medical gelat in has longer effect than 10% medical gelatin. Toxoallergic and inflam matory changes were not observed in the eyes injected with 10% and 15% medical gelatin. In the same eyes, histologically and by electron mic roscopy, were not found any changes in the layers of the cornea and re tina. These substances could be used as viscosubstances and as instrum ents in surgical interventions of the anterior eye segment and in the posterior eye segment (vitrectomy).