Until only very recently, the occurrence of schizophrenia in childhood
and early adolescence had been largely neglected. Improved diagnostic
formulations have resulted in clarification of the boundaries between
childhood schizophrenia, other psychotic disorders, and pervasive dev
elopmental disorder. The study of schizophrenia in childhood or adoles
cence provides a unique opportunity to examine illness characteristics
in the absence of the confounds of substance abuse illness, chronicit
y, and medication effects. Additionally, current etiopathologic models
of schizophrenia can be tested in this patient subgroup.