Genetic regulatory networks are complex, involving tens or hundreds of
genes and scores of proteins with varying dependencies and organizati
ons. This invites the application of artificial techniques in coming t
o understand natural complexity. I describe two attempts to deploy art
ificial models in understanding natural complexity. The first abstract
s from empirically established patterns, favoring random architectures
and very general constraints, in an attempt to model developmental ph
enomena. The second incorporates detailed information concerning the g
enetic structure, organization, and dependencies in actual systems in
an attempt to explain developmental differences. The results offered b
y these models, pitched at these different levels of abstraction, are
different. The more detailed models are more continuous with classical
developmental approaches.