OBJECTIVE - To estimate prevalence of type 2 diabetes and impaired glu
cose tolerance (IGT) among a population of native Hawaiians in two rur
al communities. RESEARCH DESIGN AND METHODS - Prevalence of glucose in
tolerance was assessed in two rural communities by history (confirmed
by record review) or with a 75-g oral glucose tolerance test according
to World Health Organization criteria. Anthropometric and demographic
data were also obtained. A short survey was used to estimate the prev
alence of known diabetes among nonparticipants. Prevalence rates were
adjusted using the standard world population of Segi. RESULTS - A tota
l of 574 native Hawaiians age greater than or equal to 30 years partic
ipated. The crude prevalence of IGT and type 2 diabetes were 15.5 and
20.4%, respectively. Only IGT prevalence was significantly higher (P =
0.03) among women (18.7%) than among men (10.9%). Prevalence of gluco
se intolerance was significantly associated with BMI, waist circumfere
nce, and waist-to-hip ratio (WHR). After adjusting for age and BMI, wa
ist circumference and WHR were significantly and independently associa
ted with type 2 diabetes prevalence only among women. Prevalence of ty
pe 2 diabetes was not significantly associated with the percentage of
Hawaiian ancestry after adjusting for age. CONCLUSIONS - This study ob
served a high prevalence of glucose intolerance associated with being
overweight among native Hawaiians. Age-adjusted type 2 diabetes preval
ence was four times higher than among the U.S. National Health. and Nu
trition Examination Survey (NHANES) II population. Prevalence was high
despite high rates of admixture with other ethnic groups of Hawaii, s
uggesting that these other Asian and Pacific Island populations share
similar susceptibility to type 2 diabetes risk.