M. Nakayama et al., ANTIPHOSPHOLIPID ANTIBODY SYNDROME IN A CASE WITH REDO CORONARY-ARTERY BYPASS-GRAFTING UNDER CARDIOPULMONARY BYPASS, SURGERY TODAY-THE JAPANESE JOURNAL OF SURGERY, 28(4), 1998, pp. 423-426
A patient who underwent redo coronary artery bypass grafting developed
severe thrombocytopenia, A platelet transfusion caused recurrent hypo
tension and hypoxia. The patient status was complicated by a systemic
thrombosis including coronary graft occlusion and central vein thrombo
sis. We found that the lupus anticoagulant, as well as other autoimmun
e antibodies, was positive only after the thrombotic episode developed
, Even though the lupus anticoagulant returned to negative about 2 mon
ths after the episode of graft occlusion, the patient eventually died
of heart failure.