Antibiotic resistance in respiratory pathogens has dramatically increa
sed during recent years. Resistance to penicillin and multiple antimic
robial agents in pneumococci and resistance to ampicillin in Moraxella
catarrhalis and Haemophilus influenzae, as a result of betalactamase
production, have become highly prevalent worldwide. The emergence of m
ultiple drug-resistant tuberculosis in different countries is of conce
rn, and has become a therapeutic challenge. (C) 1998 Rapid Science Ltd
.