Aims-To determine the prevalence of gastrointestinal symptoms in child
ren with eczema and the association of such symptoms with the extent o
f eczema or skin prick test results. Methods-Sixty five children with
atopic eczema and a control group matched for age and sex were recruit
ed. Their parents completed a questionnaire about the children's gastr
ointestinal symptoms. children's skin was examined; weight, height, an
d abdominal circumference were measured; and skin prick tests were car
ried out. Results-Gastrointestinal symptoms, especially diarrhoea, vom
iting, and regurgitation, were more common in the children with eczema
. Diarrhoea appeared to be associated with the ingestion of specific f
oods. Gastrointestinal symptoms were related to diffuse eczema and pos
itive skin prick tests to foods. There was no anthropometric differenc
es between the patient and control groups. Conclusions-A gastrointesti
nal disorder is common in children with eczema, especially with diffus
e distribution. This may be responsible for substantial symptoms and m
ay play a part in the pathogenesis of the disease and in the failure t
o thrive with which it is sometimes associated.