INDUCTION OF LUTEOLYSIS IN MARES UTILIZING A MICRO-DOSE OF PROSTAGLANDIN-F2-ALPHA IN THE SACRAL LUMBAR SPACE

An experiment was conducted to examine the luteolytic effectiveness of using low or micro doses of PGF(2 alpha) when administered at the BAI HUI acupuncture point, which is frequently used to treat ovarian dist urbances in veterinary acupuncture. The results indicate that PGF(2 al pha) given at a very low micro dose of 0.5 mg (one tenth the conventio nal recommended dose) administered at the BAI HUI acupuncture point lo cated at the sacral lumbar space is equally effective at inducing lute olysis in mid-luteal phase mares as conventional PGF(2 alpha) i.m. tre atment using a tenfold higher dose. Therefore, based on the results of the present study, nest that the BAI HUI sacral lumbar route somehow we suggest that the BAI HUI sacral lumbar route somehow provides an ex tremely efficient pathway for the drug to the ovarian level.