TOTAL SYNTHESIS OF METHYL PICROTOXATE VIA THE PALLADIUM-CATALYZED ENYNE CYCLOISOMERIZATION REACTION

Authors
KRISCHE MJ TROST BM
Citation
Mj. Krische et Bm. Trost, TOTAL SYNTHESIS OF METHYL PICROTOXATE VIA THE PALLADIUM-CATALYZED ENYNE CYCLOISOMERIZATION REACTION, Tetrahedron, 54(15), 1998, pp. 3693-3704
Citations number
20
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
15
Year of publication
1998
Pages
3693 - 3704
Database
ISI
SICI code
0040-4020(1998)54:15<3693:TSOMPV>2.0.ZU;2-N
Abstract
Bifurcation of the synthetic pathway affording total syntheses of picr otoxinin, picrotin and corianin from a common synthetic intermediate d erived via the palladium catalyzed enyne cycloisomerization leads to t he total synthesis of the picrotoxane sesquiterpene methyl picrotoxate . (C) 1998 Elsevier Science Ltd. All rights reserved.