Jl. Deaton et al., EARLY TRANSVAGINAL ULTRASOUND FOLLOWING AN ACCURATELY DATED PREGNANCY- THE IMPORTANCE OF FINDING A YOLK-SAC OR FETAL HEART MOTION, Human reproduction, 12(12), 1997, pp. 2820-2823
Our goals were to determine the prognostic value of a yolk sac or feta
l heart motion seen during an early accurately dated transvaginal ultr
asound (TVU), We reviewed 225 consecutive pregnancies for fetal heart
motion data, Furthermore, 63 pregnancies following in-vitro fertilizat
ion were reviewed for yolk sac information, The TVU was performed betw
een 5 and 6 weeks following presumed conception (heart motion data) an
d between 22 and 32 days following in-vitro fertilization (yolk sac da
ta). Pregnancies were followed until an ongoing pregnancy or spontaneo
us abortion was documented, The presence of a yolk sac between 22 and
32 days from fertilization was associated with the development of feta
l heart motion in 94% of cases, The absence of the yolk sac by 32 days
after fertilization was always associated with a poor outcome. In wom
en <36 years of age, the presence of fetal heart motion was associated
with a spontaneous abortion in only 3.5% of the cases, However, the i
ncidence of spontaneous abortion following fetal heart motion increase
d to 10% in women 36-39 years and 29% in women greater than or equal t
o 40 years of age. The presence of heart motion should not be consider
ed a reassuring sign in the older woman, These data have implications
regarding early embryology and the counselling of infertility patients
.