Am. Farrell et al., ACQUIRED ICHTHYOSIS, ALOPECIA AND LOSS OF HAIR PIGMENT ASSOCIATED WITH LEIOMYOSARCOMA, JEADV. Journal of the European Academy of Dermatology and Venereology, 10(2), 1998, pp. 159-163
Acquired ichthyosis is an important clinical finding; internal maligna
ncy, systemic disease and medication are recognised associations. We p
resent a 70-year-old lady with acquired ichthyosis and leiomyosarcoma,
one of the less frequently associated malignancies. An additional unu
sual finding was generalised thinning and loss of pigment affecting he
r hair. Scalp biopsy showed histological evidence of ichthyosis. Follo
wing resection of the tumour the ichthyosis resolved and there was reg
rowth of darker hair. (C) 1998 Elsevier Science B.V.