During the terminal incubation period of severe mumps infection, a 40-
year-old patient suffered from large infarction in the right middle ce
rebral artery territory. The proximal right internal carotid artery (I
CA) was occluded on angiography. Computed tomography of the neck detec
ted a hemorrhage located ventromedial to the right common carotid arte
ry. Four months later the right ICA was partly recanalized. Carotid su
rgery revealed an atherosclerotic plaque and a vessel wall, which was
fragile and less compact than usually. A strong inflammatory reaction
to mumps infection may have contributed to the pathogenesis of the cer
vical hemorrhage and to acute thrombosis and occlusion of the ICA. (C)
1998 Elsevier Science B.V.