In the German mutlicentre ANI study comparing continuous prophylactic
treatment with intermittent medication,the social situation of a large
sample of 364 schizophrenic patients was investigated and followed up
over a 2-year period of outpatient aftercare. Effective therapy and p
rophylaxis substantially reduced relapses and rehospitalization. On th
e other hand, the psychosocial situation still showed considerable dis
advantages. Of the patients (35 years old on average), 60% were still
unmarried. Almost one-half of the patients still lived alone or with t
heir parents, and one-third lived a very solitary life. At the end of
the 2-year aftercare period, one-third was able to earn their own livi
ng. Almost one-half retired early from their occupations. Predictors a
nd intervening variables are presented in order to stimulate early reh
abilitation approaches. Schizophrenics are particularly placed at a di
sadvantage by tighter competition in the employment market, even thoug
h the course of illness can be improve. Social psychiatry must to be i
nvolved in helping to improve social contacts, accommodation and emplo
yment in order to prevent major distress.