SYNTHESIS OF (2R)-N-BOC-2-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID USING TRIFLUOROMETHYLATION OF GARNER ALDEHYDE

Authors
QING FL PENG S HU CM
Citation
Fl. Qing et al., SYNTHESIS OF (2R)-N-BOC-2-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID USING TRIFLUOROMETHYLATION OF GARNER ALDEHYDE, Journal of fluorine chemistry, 88(1), 1998, pp. 79-81
Citations number
11
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Journal of fluorine chemistry → ACNP
ISSN journal
00221139
Volume
88
Issue
1
Year of publication
1998
Pages
79 - 81
Database
ISI
SICI code
0022-1139(1998)88:1<79:SO(AUT>2.0.ZU;2-X
Abstract
Synthesis of enantiomerically pure (2R)-N-Boc-2-amino-4,4,4-trifluorob utanoic acid (1) is described. The key step is trifluoromethylation of Garner's aldehyde. (C) 1998 Elsevier Science S.A. All rights reserved .