HUMAN OROSOMUCOID (ORM1) SUBTYPING - FURTHER POPULATION GENETIC DATA AND REPORTS ON THE FEASIBILITY TO TYPE AGED BLOOD-SAMPLES AND STAINS

Authors
DULMER M REKER G NGUYEN TT HENKE L HENKE J
Citation
M. Dulmer et al., HUMAN OROSOMUCOID (ORM1) SUBTYPING - FURTHER POPULATION GENETIC DATA AND REPORTS ON THE FEASIBILITY TO TYPE AGED BLOOD-SAMPLES AND STAINS, Journal of forensic sciences, 43(2), 1998, pp. 413-416
Citations number
20
Categorie Soggetti
Medicine, Legal
Journal title
Journal of forensic sciences → ACNP
ISSN journal
00221198
Volume
43
Issue
2
Year of publication
1998
Pages
413 - 416
Database
ISI
SICI code
0022-1198(1998)43:2<413:HO(S-F>2.0.ZU;2-A
Abstract
Genetic polymorphism of serum orosomucoid (ORM1) was investigated in 1 072 unrelated German Caucasians using isoelectric focusing followed by Western blotting and ELA. The estimated allele frequencies were ORM1 F1 = 0,5690, ORM1 S = 0,3927, ORM1 *F2 = 0,0368, ORM1 *F2S = 0,0009 a nd ORM1 F5 = 0,0005. The method was successfully applied to determine ORM1 phenotypes in aged blood samples and blood stains. The results i ndicated that the ORM protein is a informative and remarkably robust b lood group system.