GRANULOMATOSIS DISCIFORMIS MIESCHER

We describe granulomatosis disciformis Miescher in a 57-year old Femal e patient with typical clinical manifestation:disc-shaped plaques with slight central sclerosis and lesions resembling necrobiosis lipoidica and granuloma anulare. Histology revealed an infiltrate mainly compos ed of macrophages and lymphocytes and small Foci of necrobiotic collag en and of new collagen formation. We review the literature on granulom atosis disciformis and nosology, concluding - as do most authors - tha t granulomatosis disciformis is a characteristic variant within the sp ectrum of cutaneous noninfectious granulomatous disease lying in betwe en generalized granuloma anulare and necrobiosis lipoidica.