The use of quality of life assessments in clinical trials and general
medical settings has proliferated, though the conceptualization of qua
lity of life, and the cognitive processes underlying its judgement, ha
ve been neglected. To meet the needs of outcome assessments, available
assessment tools currently mix function, affect, and quality of life
items within the same scales. A process-oriented approach to quality o
f life disentangles determinants of quality of life (such as affect an
d function) from judgements of quality of life. The process model addr
esses three issues: (1) how patients attribute symptoms, emotions, and
functioning to disease or treatment; (2) how individuals interpret an
d assign meaning to physical and emotional sensations; and (3) how pat
ients integrate their assessments into overall quality of life judgeme
nts. Thus, in this model, the very same symptoms can be interpreted by
one patient as detracting from quality of life, while another patient
may see them as positively contributing to quality of life. Studies o
f quality of life and cancer are used to illustrate the model.