SYNTHESIS, NMR, RELAXOMETRY AND CIRCULARLY-POLARIZED LUMINESCENCE STUDIES OF MACROCYCLIC MONOAMIDETRIS(PHOSPHINATE) COMPLEXES BEARING A REMOTE CHIRAL CENTER

Lanthanide complexes of macrocyclic monoamidetris(phosphinate) ligands are partially hydrated in aqueous solution. Introduction of a chiral centre into the amide group leads to the formation of only two non-int erconverting complex diastereoisomers (2:1 for alpha-phenylethyl and 4 :1 for alpha-1-naphthylethyl). Proton, P-31 NMR and circularly polaris ed luminescence studies indicated that the configuration at the chiral carbon centre determines the helicity of the layout of the pendent ar ms and the macrocyclic ring conformation, with an RRR or SSS configura tion preferred at the phosphorus centres.