REACTIONS OF ORO[2-(DIMETHYLAMINOMETHYL)PHENYL-C-1,N]GOLD(III), [AU(DAMP-C-1,N)CL-2], WITH HETEROCYCLIC THIOLS - EVIDENCE FOR AU-N BOND-CLEAVAGE AND PROTONATION OF THE DIMETHYLAMINO GROUP
U. Abram et al., REACTIONS OF ORO[2-(DIMETHYLAMINOMETHYL)PHENYL-C-1,N]GOLD(III), [AU(DAMP-C-1,N)CL-2], WITH HETEROCYCLIC THIOLS - EVIDENCE FOR AU-N BOND-CLEAVAGE AND PROTONATION OF THE DIMETHYLAMINO GROUP, Journal of the Chemical Society. Dalton transactions, (6), 1998, pp. 1011-1019
loro[2-(dimethylaminomethyl)phenyl-C-1,N]gold(III) [Au(damp-C-1,N)Cl-2
], reacts with 2-mercapto-1,3-thiazoline (HSthiaz), 2-mercaptopyridine
(HSpy), sodium 1-methylmercaptotetrazolate (NaSmetetraz), 4-methyl-3-
mercapto-1,2,4-triazole (HSmetriaz) or 6-mercaptopurine (HSpur) under
cleavage of the Au-N bond and protonation of the dimethylamino group.
Compounds of general formulae [Au(Hdamp-C-1)Cl(HL)(2)](2+) (HL = HSthi
az or HSpy), [Au(Hdamp-C-1)Cl(L)] (L = Spur(-)) or [Au(Hdamp-C-1)(L)(3
)] (L = Smetetraz(-)) have been isolated and characterized. The reacti
on with HSmetriaz leads to a rapid reduction of the metal and the form
ation of the gold(I) complex [Au(HSmetriaz) (2)](+). The crystal struc
tures of [Au(Hdamp-C-1)Cl(HSthiaz)(2)]Cl-2 . Me2CO, [Au(Hdamp-C-1)Cl(H
Spy)(2)]. H2O, [Au(Hdamp-C-1)(Smetetraz)(3)] and [Au(Hdamp-C-1)Cl(Spur
)]Cl have been elucidated showing the gold atoms in distorted square-p
lanar co-ordination environments. Generally, one or more hydrogen atom
s of the heterocyclic ligands and/or the NMe2H+ group form hydrogen bo
nds in the solid-state structures. The reaction of Na[AuCl4] with Na(S
metetraz) and [NEt4]Br yields bright red crystals of [NEt4][Au(Smetetr
az)(4)], the first structurally characterized gold(III) complex with f
our monodentate thiolate ligands. The structure of the complex shows w
ell separated [Au(Smetetraz)(4)](-) anions with Au-S distances of 2.35
4(4) Angstrom.