3 NAPHTHALENES FROM ROOT BARK OF HIBISCUS-SYRIACUS

Authors
YOO ID YUN BS LEE IK RYOO IJ CHOUNG DH HAN KH
Citation
Id. Yoo et al., 3 NAPHTHALENES FROM ROOT BARK OF HIBISCUS-SYRIACUS, Phytochemistry, 47(5), 1998, pp. 799-802
Citations number
10
Categorie Soggetti
Biology,"Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
47
Issue
5
Year of publication
1998
Pages
799 - 802
Database
ISI
SICI code
0031-9422(1998)47:5<799:3NFRBO>2.0.ZU;2-B
Abstract
Three new naphthalenes, designated as syriacusins A-C, were isolated f rom the root bark of Hibiscus syriacus. These compounds were identifie d as roxy-6-methyl-8-methoxy-1-naphthalenecarbaldehyde, oxymethyl-7,8- dimethoxy-1-naphthalenecarbaldehyde, dihydroxy-6-methyl7-methoxynaphth alenecarbolactone (1 --> 8), respectively, on the basis of various spe ctral studies. The compounds inhibited lipid peroxidation with IC(50)s of 0.54, 5.90 and 1.02 mu g ml(-1), respectively. The first compound also showed cytotoxicity against some human cancer cell lines with an ED50 of 1.5-2.4 mu g ml(-1). (C) 1998 Elsevier Science Ltd. All rights reserved.