OCHRATOXIN-A ACTS AS A PHOTOACTIVATABLE DNA-CLEAVING AGENT

Authors
GILLMAN IG YEZEK JM MANDERVILLE RA
Citation
Ig. Gillman et al., OCHRATOXIN-A ACTS AS A PHOTOACTIVATABLE DNA-CLEAVING AGENT, Chemical communications, (6), 1998, pp. 647-648
Citations number
23
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
6
Year of publication
1998
Pages
647 - 648
Database
ISI
SICI code
1359-7345(1998):6<647:OAAAPD>2.0.ZU;2-S
Abstract
The ability of ochratoxin A to photoinduce DNA cleavage is described; in the presence of DNA the photoreaction yields the non-chlorinated de rivative, ochratoxin B, while a hydroquinone derivative is produced un der anaerobic conditions.