Few patients with prostate cancer metastatic to the lymphnodes can be
cured by radiotherapy, radical prostataectomy or androgen deprivation.
Inevitably serum PSA levels will rise after a few years whereas the c
linical recurrence appears after 5 to 10 years. Prospective trials reg
arding adjuvant treatment of lymphnode positive prostate cancer do not
exist. Retrospective studies involving adjuvant endocrine treatment r
eveal a prolonged disease free survival time. Scientific proof of the
best treatment for prostate cancer with lymphnode metastasis does not
exist. The decision how to treat is based on our personal experience a
nd philosophy as well as on our knowledge and interpretation of the av
ailable lierature. The art of medicine is the feeling for the best tre
atment of each individual patient.