FAMILIAL HEMIPLEGIC MIGRAINE WITH IRREVERSIBLE BRAIN-DAMAGE

Familial hemiplegic migraine (FHM) is an autosomal dominant syndrome c haracterized by recurrent episodes of varying degrees of hemiparesis a ssociated with migraine. The aura including hemiparesis may be prolong ed and in severe attacks may often be associated with confusion or com a, We describe a case of FHM whose aura was atypically prolonged and r esulted in irreversible brain deficit which on magnetic resonance imag ing (MRI) was suggestive of cortical hyperperfusion. A subsequent MRI showed left brain atrophy.