MICACOCIDIN-A, MICACOCIDIN-B AND MICACOCIDIN-C, NOVEL ANTIMYCOPLASMA AGENTS FROM PSEUDOMONAS SP. - II - STRUCTURE ELUCIDATION

Metal-containing novel heterocyclic antibiotics, micacocidin A (1), B (2), and C (3) have been isolated from the culture filtrate of Pseudom onas sp. No. 57-250. The structure and absolute configuration of micac ocidin A, an octahedral Zn2+ complex, was determined by X-ray crystall ographic analysis. And then, the structures of the two congeners, mica cocidin B (Cu2+ complex) and C (Fe3+ complex) were investigated by emp loying one dimensional and two dimensional homonuclear and heteronucle ar NMR spectroscopies and mass spectrometry.