After heat, conductivity has been described as the second most inactiv
ating factor of viruses in surface waters. Using poliovirus-1, we show
ed that a highly significant linear relationship between virus inactiv
ation rate and water conductivity can be obtained for most of the test
ed sterilized water samples. Using sterile saline solutions, we demons
trated that this apparent relationship is false, i.e., virus inactivat
ion rate is not affected by water conductivity alone. With the hypothe
sis that salts may serve to potentiate the antiviral activities of cer
tain microbiological substances that are supposed to be found in the t
ested samples, we can explain the apparent relationship observed in th
is study and in similar ones. As a consequence, an effective water tre
atment could be responsible for the removal of both viruses and some v
irus-inactivating factors. Alternatively, virus-inactivating capabilit
y of a given water resource could be enhanced along with its hardness
or its degree of mineralization.