Je. Tamis et Js. Steinberg, VALUE OF THE SIGNAL-AVERAGED P-WAVE ANALYSIS IN PREDICTING ATRIAL-FIBRILLATION AFTER CARDIAC-SURGERY, Journal of electrocardiology, 30, 1997, pp. 36-43
Atrial fibrillation (AF) is the most common sustained arrhythmia occur
ring after cardiac surgery. Beside important implications regarding pa
tient recovery, AF has been shown to substantially lengthen hospital s
tay-our recent study found a 3-day prolongation after adjusting for al
l other significant factors. Identification of those at highest risk o
f AF by clinical or noninvasive characteristics may be a useful strate
gy for targeted prophylactic therapy. Our data have shown that prolong
ed atrial conduction as assessed by analysis of the P wave duration fr
om the signal-averaged electrocardiogram (SAECG) imparts a four fold i
ncrease in risk for postoperative AF, independently of other measured
variables. Ln addition, abnormal conduction was present on the preoper
ative P wave ECG (P-SAECG), implying a prexisting substrate that is tr
iggered by surgery. The use of combination abnormal noninvasive variab
les (eg, abnormal P-SAECG and lo iv left ventricular ejection fraction
) can identify groups with a 50% risk of AF, which is nine times as hi
gh as when both tests are normal. Thus, the P-SAECG is a useful and ac
curate predictor of AF after cardiac surgery.