THE ANTITUSSIVE ACTIVITY OF GUIERA-SENEGALENSIS GMEL,J.F. (COMBRETACEAE)

Authors
SANOGO R DEPASQUALE R GERMANO MP
Citation
R. Sanogo et al., THE ANTITUSSIVE ACTIVITY OF GUIERA-SENEGALENSIS GMEL,J.F. (COMBRETACEAE), PTR. Phytotherapy research, 12(2), 1998, pp. 132-134
Citations number
15
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
12
Issue
2
Year of publication
1998
Pages
132 - 134
Database
ISI
SICI code
0951-418X(1998)12:2<132:TAAOGG>2.0.ZU;2-8
Abstract
The leaf decoction of Guiera senegalensis possesses an antitussive act ivity. The antitussive activity of Guiera was evaluated using the clas sical citric acid-evoked cough model in guinea-pigs. The leaf decoctio n of the leaves of Guiera dose-dependently decreased the number of cou ghs. The cytotoxicity test showed that the acute cytotoxic concentrati on of Guiera decoction was >1000 mu g/mL. (C) 1998 John Wiley & Sons, Ltd.