PHARMACOLOGICAL STUDIES OF STRIGA-SENEGALENSIS BENTH (SCROPHULARIACEAE) AS AN ABORTIFACIENT

Authors
CHOUDHURY MK PHILLIPS AL MUSTAPHA A
Citation
Mk. Choudhury et al., PHARMACOLOGICAL STUDIES OF STRIGA-SENEGALENSIS BENTH (SCROPHULARIACEAE) AS AN ABORTIFACIENT, PTR. Phytotherapy research, 12(2), 1998, pp. 141-143
Citations number
6
Categorie Soggetti
Chemistry Medicinal","Pharmacology & Pharmacy
Journal title
PTR. Phytotherapy research → ACNP
ISSN journal
0951418X
Volume
12
Issue
2
Year of publication
1998
Pages
141 - 143
Database
ISI
SICI code
0951-418X(1998)12:2<141:PSOSB(>2.0.ZU;2-N
Abstract
The methanal extract of Striga senegalensis Benth (Scrophulariaceae) w as investigated an isolated rat uterus; Acetylcholine and the methanal extract of the plant produced dose related contractions of smooth mus cle of the isolated rat uterus in vitro. Atropine in doses of 2 x 10(- 2) to 32 x 10(-2) mu g/mL antagonized dose dependently the contraction of the isolated rat uterus produced by both acetylcholine (1.6 x 10(- 1) mu g/mL) and the methanal extract (160 mu g/mL). (C) 1998 John Wile y & Sons, Ltd.