Dl. Forman et al., BREAST RECONSTRUCTION IN PREVIOUSLY IRRADIATED PATIENTS USING TISSUE EXPANDERS AND IMPLANTS - A POTENTIALLY UNFAVORABLE RESULT, Annals of plastic surgery, 40(4), 1998, pp. 360-363
There exists a paucity of definitive information on the suitability or
implant reconstructions in previously Irradiated breast cancer patien
ts. This controversial topic prompted a review of our prosthetic recon
structions in this select group of patients. A retrospective study of
patients treated between 1976 and 1993 with lumpectomy and radiation t
herapy far early breast cancer revealed 67 patients with local recurre
nces, Nine of these pa tients (10 breasts) underwent a two-stage prost
hetic reconstruction following a salvage mastectomy. The average age w
as 47.9 years. The mean dose of irradiation was 6,070 cGy, The average
interval from radiation therapy to placement of a tissue expander was
4.6 years, In one patient (10%) the tissue expander extruded, The ave
rage follow-up for 8 patients (9 breasts) who underwent exchange to a
permanent, prosthesis was 5.1 years. In four reconstructions (40%) the
re was an uneventful postoperative course. Two cases (20%) were diffic
ult to expand and the final result lacked projection, One patient (10%
) developed an infection requiring removal of the permanent prosthesis
, Two patients (20%) developed Baker class III or IV capsular contract
ures. Overall, in our group of 10 implant reconstructions, 60% of the
patients resulted in either a complication or an unfavorable result.