Vh. Deshpande et B. Rai, SYNTHESIS OF (S)-(-)DI-O-METHYL-M5032, Indian journal of chemistry. Sect. B: organic chemistry, including medical chemistry, 36(12), 1997, pp. 1172-1174
Synthesis of (S)-(-)-di-O-methyl-M5032 9 has been described by esterif
ication of 3,5-dimethoxyphenylacetyl chloride 7 with t-butyl (S)-5-hyd
roxy-2(E)-hexenoate 6 followed by intramolecular acylation.