THE LACK OF AGE AS A SIGNIFICANT PROGNOSTIC FACTOR IN NONMETASTATIC BREAST-CANCER

Aims. To determine the prognostic significance of age at diagnosis in women with non-metastatic breast cancer. Methods. A retrospective revi ew of all newly diagnosed breast cancer in women between 1975 and 1991 was carried out at a tertiary Oncology Referral Centre. Patients were divided into three age groups: <40 years, 40-50 years and >50 years. Demographic and management/outcome details were collected from patient s with UICC stages I-III. The effect of age on overall and relapse fre e survival was analysed by standard statistical methods. Results. Of 1 289 new cases registered during the study period, 710 (55%) were UICC stages I-III. Of the latter group 250 (35%) women were in the age grou p of less than 40 years, 237 (33%) were between 40 and 50 years and 22 3 (32%) were older than 50 years. Women from the younger age group had a higher proportion of breast-conserving surgery, and adjuvant chemo- and radiation therapy, while the proportion of hormone therapy usage w as higher in older women. There was no difference in overall survival (P=0.64) and relapse-free survival (P=0.53) between the three age grou ps. Conclusion. In this study, age was not a prognostic factor in pred icting overall or relapse-free survival in women with breast cancer.