Phacoemulsification-aspiration (PEA) followed by peripheral iridectomy
was performed in 10 patients, and the dissected iris fragments were e
xamined by electron microscopy. Organic changes such as cytoplasmic va
cuolation and lamellar formation were observed in both the sphincter a
nd dilator muscles of the pupil. No changes in the axons were detected
. The same findings were observed when a simian eye was examined after
PEA. These results indicate that PEA causes injury to iris muscles.