ORBITAL TUMOR IN ACUTE MYELOID-LEUKEMIA ASSOCIATED WITH KARYOTYPE 46,XX,T(8-21)(Q22-Q22) - A CASE-REPORT

Orbital tumor formation in acute myeloid leukemia (AML) is rare as an initial symptom. Furthermore, orbital granulocytic sarcoma (myeloid sa rcoma) in pediatric patients is uncommon. We describe a 5-year-old Jap anese girl with a left orbital mass as an initial symptom of AML, the mass revealed by computed tomograph. Periperal blood and bone marrow p ictures and a chromosomal analysis disclosing 46,XX,t(8;21)(q22;q22) s howed AML (M2 according to the French-American-British classification) . She was treated with antileukemic chemotherapy systemically. Three w eeks after the initiation of chemotherapy, the orbital tumor regressed markedly. AML as an initial symptom of the orbital mass should be ful ly considered in a differential diagnosis, even in the absence of typi cal leukemic symptoms, and chromosomal analysis and immunophenotypical analysis may explain the pathogenesis of the extramedullary leukemic tumor.