A 28-year-old male patient in good health with no previous neurologic
or ophthalmoscopic abnormalities developed right homonymous hemianopsi
a. Magnetic resonance (MR) imaging demonstrated bilateral high-signal
suprageniculate lesions, The lesion located in the left parieto-occipi
tal area was compatible with the field defect observed. Oligoclonal ba
nds were present in the cerebrospinal fluid, Testing of visual-evoked
potentials revealed increased latencies in both eyes. The patient was
given 1 g/day intravenous methylprednisolone for 3 days. The visual fi
elds, as determined by automated static perimetry, recovered completel
y in 2 weeks, Follow-up MR imaging at 1 month showed no change compare
d to baseline, Seven months after the initial attack he suffered right
internuclear ophthalmoplegia, which resolved spontaneously within 1 w
eek, Based on the clinical and radiologic findings, the final diagnosi
s was made as clinically definite multiple sclerosis (MS). This patien
t represents a rare case of MS presenting first with homonymous hemian
opsia.