CENTRAL DIABETES INSIPITUS IN A PATIENT WITH CONGENITAL TOXOPLASMOSIS

A 33-day-old male infant who developed central diabetes insipitus as a complication of congenital toxoplasmosis is presented. He had polyuri a and hypernatremia on admission and responded to Intranasal desmopres sin acetate with the normalization of abovementioned findings. Compute d tomographic (CT) scan of the brain showed obstructive hydrocephaly w ith periventricular and right basal ganglion calcification. CT scan of the pituitary gland, thyroid function tests, and serum cortisol level s were all normal. This is the first report of isolated diabetes insip itus with congenital toxoplasmosis in literature and central diabetes insipitus should be remembered if polyuria and hypernatremia develops in a patient with congenital toxoplasmosis.