Methanol, a highly toxic substance, is used as an industrial solvent a
nd in automobile antifreeze. Acute methanol poisoning produces severe
metabolic acidosis and serious neurologic sequelae. We describe a 50-y
ear-old woman with accidental methanol intoxication who was in a veget
ative state. MRI showed haemorrhagic necrosis of the putamina and oede
ma in the deep white matter.