W. Millesi et al., RECONSTRUCTION OF THE FLOOR OF THE MOUTH WITH A FASCIAL RADIAL FOREARM FLAP, PRELAMINATED WITH AUTOLOGOUS MUCOSA, International journal of oral and maxillofacial surgery, 27(2), 1998, pp. 106-110
To circumvent the disadvantages of extraoral skin within the oral cavi
ty and to cover mucosal defects by mucosa, we successfully prelaminate
d the radial forearm flap by insertion of buccal mucosa in ten patient
s. In a first-step operation, free grafts of buccal mucosa were fixed
to the forearm fascia and covered with an alloplastic sheet, separatin
g the mucosa grafts and the dissected fascia between and around the gr
afts from the overlaying subcutaneous tissue. The dimension of the all
oplastic sheet in the subcutaneous pocket was chosen according to the
size of the desired flap. Underneath the alloplastic sheet, the mucosa
l grafts merged and the mucosal surface increased by advancing of epit
helial cells under in vivo culture conditions. After two months, mucos
al prelamination of the distal radial forearm fascia had led to thin,
pliable and resistant fasciomucosal flaps with a mucosal surface up to
7x4 cm, allowing physiological intraoral reconstruction. The preserva
tion of skin and subcutaneous tissue of the forearm also enabled prima
ry wound closure, reducing donor-site morbidity.