H. Nagashima et al., MONITORING OF CEREBRAL HEMODYNAMICS USING NEAR-INFRARED SPECTROSCOPY DURING LOCAL INTRAARTERIAL THROMBOLYSIS - CASE-REPORT, Surgical neurology, 49(4), 1998, pp. 420-424
BACKGROUND The efficacy of continuous measuring of changes in regional
cerebrovascular hemoglobin saturation during local intraarterial thro
mbolytic therapy for middle cerebral artery (MCA) occlusion is discuss
ed. METHODS To obtain real-time data on changing cerebral hemodynamics
, near-infrared spectroscopy (NIRS) was used during recanalization of
an occluded MCA branch. Changes in regional cerebrovascular hemoglobin
saturation of the affected left frontal lobe were observed immediatel
y after intraarterial injection of urokinase (UK). RESULTS A steady in
crease in regional oxygen saturation (rSO2) was observed until recanal
ization was confirmed angiographically as a result of 300,000 IU of UK
. CONCLUSIONS Monitoring of cerebrovascular hemoglobin saturation by N
IRS is a simple, noninvasive technique suggesting its potential for in
traoperative monitoring during interventional neuroradiologic procedur
es, (C) 1998 by Elsevier Science Inc.