MONITORING OF CEREBRAL HEMODYNAMICS USING NEAR-INFRARED SPECTROSCOPY DURING LOCAL INTRAARTERIAL THROMBOLYSIS - CASE-REPORT

BACKGROUND The efficacy of continuous measuring of changes in regional cerebrovascular hemoglobin saturation during local intraarterial thro mbolytic therapy for middle cerebral artery (MCA) occlusion is discuss ed. METHODS To obtain real-time data on changing cerebral hemodynamics , near-infrared spectroscopy (NIRS) was used during recanalization of an occluded MCA branch. Changes in regional cerebrovascular hemoglobin saturation of the affected left frontal lobe were observed immediatel y after intraarterial injection of urokinase (UK). RESULTS A steady in crease in regional oxygen saturation (rSO2) was observed until recanal ization was confirmed angiographically as a result of 300,000 IU of UK . CONCLUSIONS Monitoring of cerebrovascular hemoglobin saturation by N IRS is a simple, noninvasive technique suggesting its potential for in traoperative monitoring during interventional neuroradiologic procedur es, (C) 1998 by Elsevier Science Inc.