Long-term results of chronic upper limb ischemia and related prognosti
c factors were evaluated. In addition, the efficacy of endoscopic thor
acic sympathectomy was examined. Thirty-one patients with chronic isch
emic episodes of 41 upper limbs were reviewed retrospectively. The cau
se of ischemia included atherosclerosis in 18 limbs, Buerger's disease
in 16 limbs, and other causes in seven limbs. Thoracic sympathectomy
was undertaken in 21 limbs, and bypass grafting was undertaken in five
limbs. Fifteen limbs were not treated surgically. Of the 21 thoracic
sympathectomies, the transthoracic approach was used in 12 and thoraco
scopy was used in seven. In addition, an extrapleural approach was use
d in two cases because of dense pleural adhesion. Compared with open s
ympathectomy, the intraoperative blood loss, the duration of chest tub
e drainage, and the complication rate were significantly decreased in
the endoscopic group. Recurrence rates for all 41 limbs were 14.5% at
1 year, 19.2% at 2 years, and 30.3% at 3 years. Univariate analysis re
vealed significantly lower recurrence rates for men, cases caused by B
uerger's disease, and limbs without contralateral upper limb ischemia.
Multivariate analysis also disclosed a significantly lower recurrence
rate for limb ischemia caused by Buerger's disease. The cause of uppe
r limb ischemia influenced the outcome. Tn cases of Buerger's disease,
the recurrence rates were low, and thoracic sympathectomy was effecti
ve. Thoracoscopic sympathectomy was safe and less invasive than open s
ympathectomy and is a valid therapeutic option for treating upper limb
ischemia.