NOVEL ASYMMETRIC-SYNTHESIS OF AN INDOLIZIDINE ALKALOID, (-LENTIGINOSINE EMPLOYING HIGHLY STEREOSELECTIVE HYDROGENATION OF ALPHA-HYDROXYPYRROLIDINE())

Authors
YODA H KAWAUCHI M TAKABE K
Citation
H. Yoda et al., NOVEL ASYMMETRIC-SYNTHESIS OF AN INDOLIZIDINE ALKALOID, (-LENTIGINOSINE EMPLOYING HIGHLY STEREOSELECTIVE HYDROGENATION OF ALPHA-HYDROXYPYRROLIDINE()), Synlett, (2), 1998, pp. 137
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
2
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):2<137:NAOAIA>2.0.ZU;2-H
Abstract
An efficient and novel process is described for the asymmetric synthes is of all (1S,2S, 8aS)-dihydroxyindolizidine alkaloid, (+)-lentiginosi ne in which the asymmetric deoxygenation of the quaternary alpha-hydro xypyrrolidine derivative derived from D-xylose is used as a key step.