A MILD, EFFICIENT, AND SELECTIVE METHOD FOR THE DESILYLATION OF MORE COMMON TRIALKYLSILYL ETHERS BY CERIUM(III) CHLORIDE HEPTAHYDRATE AND SODIUM-IODIDE IN ACETONITRILE

Authors
BARTOLI G BOSCO M MARCANTONI E SAMBRI L TORREGIANI E
Citation
G. Bartoli et al., A MILD, EFFICIENT, AND SELECTIVE METHOD FOR THE DESILYLATION OF MORE COMMON TRIALKYLSILYL ETHERS BY CERIUM(III) CHLORIDE HEPTAHYDRATE AND SODIUM-IODIDE IN ACETONITRILE, Synlett, (2), 1998, pp. 209
Citations number
22
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synlett → ACNP
ISSN journal
09365214
Issue
2
Year of publication
1998
Database
ISI
SICI code
0936-5214(1998):2<209:AMEASM>2.0.ZU;2-1
Abstract
Treatment of trialkylsilyl ethers with cerium(III) chloride heptahydra te and sodium iodide in acetonitrile provides a simple, convenient, an d chemoselective process for desilylation, and the parent alcohol was obtained in high yield. The trialkylsilyl ethers have been cleaved sel ectively in the presence of acetate, benzyl and tetrahydropyranyl ethe rs.