Ah. Atta et A. Alkofahi, ANTINOCICEPTIVE AND ANTIINFLAMMATORY EFFECTS OF SOME JORDANIAN MEDICINAL PLANT-EXTRACTS, Journal of ethnopharmacology, 60(2), 1998, pp. 117-124
The anti-nociceptive effect of ethanolic extract of 11 traditionally u
sed Jordanian plants was studied by using the acetic acid-induced writ
hing and hot-plate test in mice. The anti-inflammatory effect of these
plants was determined by xylene-induced ear oedema in mice and cotton
pellet granuloma test in rats. Mentha piperita, Cinnamomum zeylanicum
, Apium graveolens, Eucalyptus camaldulentis, and Ruta graveolens poss
ess an anti-nociceptive effect against both acetic acid-induced writhi
ng and hot plate-induced thermal stimulation. M. piperita, Jasminum of
ficinale, Commiphora molmol, and Beta vulgaris possess an anti-inflamm
atory effect against acute (xylene-induced ear oedema) and chronic (co
tton-pellet granuloma) inflammation. The anti-nociceptive and anti-inf
lammatory effects were dose dependent. These data affirm the tradition
al use of some of these plants for painful and inflammatory conditions
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