ASYMMETRIC NITROGEN - 80 - DIASTEREOMERIC DERIVATIVES OF 1-ALKOXYAZIRIDINE-2,2-DICARBOXYLIC ACIDS - SYNTHESIS, STRUCTURE, AND ABSOLUTE-CONFIGURATION

Authors
PROSYANIK AV ROZHKOV VV MOSKALENKO AS MISHCHENKO AI FORNI A MORETTI I TORRE G BRUKNER S MALPEZZI L KOSTYANOVSKY RG
Citation
Av. Prosyanik et al., ASYMMETRIC NITROGEN - 80 - DIASTEREOMERIC DERIVATIVES OF 1-ALKOXYAZIRIDINE-2,2-DICARBOXYLIC ACIDS - SYNTHESIS, STRUCTURE, AND ABSOLUTE-CONFIGURATION, Russian chemical bulletin, 47(1), 1998, pp. 119-126
Citations number
23
Categorie Soggetti
Chemistry
Journal title
Russian chemical bulletin → ACNP
ISSN journal
10665285
Volume
47
Issue
1
Year of publication
1998
Pages
119 - 126
Database
ISI
SICI code
1066-5285(1998)47:1<119:AN-8-D>2.0.ZU;2-J
Abstract
Esters and amides (including N-15 analogs) of 1-alkoxyaziridine-2,2-di carboxylic acids that contain N-alkoxy substituents ((PrO)-O-i, RO2CCH 2O, (R,S)-RO2CCH(Me)O, or (S)-RO2CCH(Me)O) were synthesized. Triamide of the last-mentioned type was isolated in the diastereomerically pure forms. The validity of the H-1 NMR criteria, which were suggested for the determination of absolute configurations of diastereomers, was co nfirmed by X-ray diffraction study of the (S,S)-form.