AJANOLIDE-A, A NEW GERMACRANOLIDE FROM AJANIA FRUTICULOSA

A new germacranolide, ajanolide A, was isolated from aerial parts of A jania fruticulosa by means of extraction with CHCl3 and adsorption chr omatography. This compound was identified as ,7S,11R)-3-acetoxygermacr a-1(10),4-dien-12,6-olide methyl-11-oxabicyclo[8.3.0]trideca-4(E),8(Z) -dien- 12-one) by X-ray diffraction analysis. 2D H-1-H-1 (COSY) and C- 13-H-1 (COSY) NMR spectroscopy was used for assigning the H-1 and C-13 NMR signals in the spectra of ajanolide A.