The authors evaluated the association between serum cholesterol levels
and social, clinical, and functional characteristics in 637 elderly h
ospitalized patients (mean age = 79.1 years, range = 65-97) from the G
eriatric Evaluation and Rehabilitation Unit (GERU) at P. Richiedei Hos
pital in Gussago, Brescia (Italy). Patients consecutively admitted to
the GERU during an 18-month period underwent a multidimensional evalua
tion inducing information on demographics, cognitive status, physical
health (number of chronic diseases and administered drugs), functional
disability, and nutritional status. Mean cholesterol levels were sign
ificantly lower in men; persons living with others; older individuals;
and individuals with cognitive impairment, poorer somatic health, hig
her disability, and a higher level of malnutrition. Lower serum choles
terol levels may be considered an independent hematologic marker of fr
ailty in elderly hospitalized patients.