MAIN PATHWAYS OF TRITIUM LABELING OF TRIAZOLOBENZODIAZEPINES

Authors
SHEVCHENKO VP NAGAEV IY POTAPOVA AV MYASOEDOV NF
Citation
Vp. Shevchenko et al., MAIN PATHWAYS OF TRITIUM LABELING OF TRIAZOLOBENZODIAZEPINES, Radiochemistry, 40(1), 1998, pp. 74-78
Citations number
18
Categorie Soggetti
Chemistry Analytical","Chemistry Inorganic & Nuclear
Journal title
Radiochemistry → ACNP
ISSN journal
10663622
Volume
40
Issue
1
Year of publication
1998
Pages
74 - 78
Database
ISI
SICI code
1066-3622(1998)40:1<74:MPOTLO>2.0.ZU;2-Y
Abstract
Tritium labeling of triazolobenzodiazepines can be performed by isotop e exchange with highly labeled tritium water at elevated temperatures. This method yields labeled compounds with the molar activity by a fac tor of 8 higher than in solid-phase isotope exchange.