TRANSLOCATION T(1-10)(Q21-Q26) IN A CASE OF ACUTE NONLYMPHOCYTIC LEUKEMIA

Authors
TERREROS MC QUESADA M SLAVUTSKY IR
Citation
Mc. Terreros et al., TRANSLOCATION T(1-10)(Q21-Q26) IN A CASE OF ACUTE NONLYMPHOCYTIC LEUKEMIA, Acta haematologica, 99(2), 1998, pp. 92-94
Citations number
14
Categorie Soggetti
Hematology
Journal title
Acta haematologica → ACNP
ISSN journal
00015792
Volume
99
Issue
2
Year of publication
1998
Pages
92 - 94
Database
ISI
SICI code
0001-5792(1998)99:2<92:TTIACO>2.0.ZU;2-P
Abstract
Chromosome banding studies carried out on bone marrow cells from a 16 year-old boy with an M1 acute nonlymphocytic leukemia (ANLL) revealed an unbalanced translocation involving chromosomes 1 and 10: der(10) t( 1;10) (q21;q26) that results in a partial trisomy 1q between bands 1q2 1-1qter. Marker del(6)(q21) and trisomies of chromosomes 18, 21 and 22 were also observed. To our knowledge, this der(10) is the first to be reported in a patient with ANLL.