MYCOTIC ENDOCARDITIS, INTRACARDIAL AND AO RTIC THROMBOSIS IN THE NEONATE - PRESENTATION OF 2 CASES

Venous and arterial thrombosis are reported more and more frequently, in newborns submitted to invasive procedures and especially to central vessel catheterization, Right atrial thrombosis has been rarely repor ted and carries no hight mortality rate. We report 2 cases of neonatal mycotic sepsis with endocarditis associated with intraatrial and aort ic thrombosis. Thrombolysis with urokinase (4400 IU/kg i.v. in 10 minu tes followed by a dose of 4000/IU/kg/hr for 12 hrs) has been effective and safe in 1 case. Serial echocardiography has been very useful by d iagnosis and monitoring during and after treatment.