FEVER - HOW MAY CIRCULATING PYROGENS SIGNAL THE BRAIN

Authors
BLATTEIS CM SEHIC E
Citation
Cm. Blatteis et E. Sehic, FEVER - HOW MAY CIRCULATING PYROGENS SIGNAL THE BRAIN, News in physiological sciences, 12, 1997, pp. 1-9
Citations number
15
Journal title
News in physiological sciences → ACNP
ISSN journal
08861714
Volume
12
Year of publication
1997
Pages
1 - 9
Database
ISI
SICI code
0886-1714(1997)12:<1:F-HMCP>2.0.ZU;2-F
Abstract
Recent data suggest that fever may be initiated by products of liver m acrophages that activate subdiaphragmatic vagal afferents. In the brai n, these inputs may be transmitted to fever-producing sites via noradr energic pathways; prostaglandin E-2 may be the ultimate pyrogenic medi ator.